Thursday, May 1, 2014

The Big deal of Big data in Healthcare


There is no doubt about that, big data has a potential of generating $38 billion annual revenue, $165 billion in clinical operations and $105 in R&D.  But, what is the big deal of big data?

According to Rob Friehl, Chairman of PerkinElmer, ⅓ of the revenue of PerkinElmer are generated from detection and imaging instruments. Detection involves using different types of data such as mass spectrometer etc. and looking at minute details. It is referred to as “finding an individual cash chip on the Vegas strip and knowing its exact chemical composition”. Big data is the new frontier in competition in the healthcare sector as it allows synthesis of large volume of data from a variety of sources at high velocity.

With the use of big data, a heel prick can detect approximately 54 million diseases and this process was used successfully on 21 million babies. Big data has enabled efficient collaboration of different research organizations across the globe and revolutionized the system by setting up a “self-service” model for scientists. Big data has allowed scientists to acquire large volumes of data and connect with other experts in the field using mature technologies.

Another key challenge faced by the healthcare system is correlation. Currently, 55% of the drugs prescribed to patients do not work and 70% of the cancer drugs prescribed to patients do not work. What is needed today is personalized healthcare that is effective and efficient.

According to Rob Friehl, 1 genome produces 240 billion bytes of data and if the interaction of our biological processes with the environment is included, then the volume of data collected significantly increases. Recent experiments have indicated the genetics and environment are not mutually exclusive but are rather interrelated.  The idea that environment plays as big a role as genetics in an individual health was confirmed by studies conducted on identical twins. The DNA of identical twins are almost identical. However, it was found that one twin might get cancer while the other is not susceptible, for example. The differences stem from chemical modifications in the genes over the years. These epigenetic effects, as they are called, are the result of chemical exposure, dietary habits and other environmental factors.

Thus, big data does not only help identify disease early by analyzing large volumes of data but can also help take precautionary measures to prevent it by providing personalized health care treatment based on epigenetics.


References

Rob Friehl, Chairman, CEO and President of PerkinElmer talks about PerkinElmer and the role big data plays in healthcare


Jeffrey Hammerbacher, Founder and Chief Scientist at Cloudera, Director at Sage Bionetworks and Assistant Professor at Mount Sinai School of Medicine, talks about Big Data 




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